Ifitm2 cancer
WebInterferon-inducible transmembrane (IFITM) proteins are a family of small homologous proteins, localized in the plasma and endolysosomal membranes, which confer cellular resistance to many viruses. In addition, several distinct functions have been associated with different IFITM family members, incl … The IFITM protein family in adaptive immunity WebIFITM2 (COSG616316) Genomic coordinates 11:307927..309392 (positive strand) Synonyms 1-8D, DSPA2c, CCDS41583.1, Q01629, ENSG00000185201.16 COSMIC-3D …
Ifitm2 cancer
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WebProduct name Anti-IFITM2 antibody Description Rabbit polyclonal to IFITM2 Host species Rabbit Tested applications Suitable for: IHC-P, WB, ICC/IF more details Species reactivity Reacts with: Human Immunogen Recombinant fragment corresponding to Human IFITM2 aa 1-100. Database link: Q01629 Run BLAST with Run BLAST with Positive control Web19 okt. 2010 · When IFITM1 and IFITM2 were combined, the sensitivity was 86% (18/21; 95% CI 64–97%) and the specificity was 96% (1/23; 95% CI 78–100%). The fecal expression analysis of IFITM1 and IFITM2 mRNA by real-time RT-PCR for CRC screening exhibited high specificities, and the sensitivity was further improved by combining IFITM1 …
Web1 jan. 2024 · The IFITM family is observed with conflicting roles in cancer: tumor-antagonizing and tumor-promoting. In hepatoma, loss of IFITM2 accelerated … WebExpression of IFITM2 (1-8D, DSPA2c) in NK-cells tissue. Antibody staining with HPA004337 in immunohistochemistry. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. ... Cancer Prognosis. Cancer ...
Web1 jan. 2024 · Notably, another study identified IFITM2 as a receptor for a secreted form of the chaperone BAG3, showing that IFITM2 mediated signaling through PI3K and p38 … Web21 mrt. 2024 · IFITM2 and IFITM3 display anti-HCV activity that may complement the anti-HCV activity of IFITM1 by inhibiting the late stages of HCV entry, possibly in a …
Web23 okt. 2015 · IFITM1 has been identified as a potent antiviral effector against hepatitis C virus (HCV), whereas the related family members IFITM2 and IFITM3 have been described to have antiviral effects against a broad range of RNA viruses.
Web28 jul. 2024 · IFITM proteins were expressed and further induced by interferons in human lung, gut, heart and brain cells. IFITM-derived peptides and targeting antibodies inhibit SARS-CoV-2 entry and replication... mcphs check dining pointsWeb29 mrt. 2024 · IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro. Predicative value of IFITM2 in renal clear cell carcinoma: IFITM2 is … lifeguard phrasesWebIFITM2 (COSG616316) Genomic coordinates 11:307927..309392 (positive strand) Synonyms 1-8D, DSPA2c, CCDS41583.1, Q01629, ENSG00000185201.16 COSMIC-3D No protein structures Number of samples 41998 unique samples 90 unique samples with mutations Alternative transcripts IFITM2_ENST00000399817, … mcphs chief of policeWeb21 mrt. 2024 · IFITM2 and IFITM3 display anti-HCV activity that may complement the anti-HCV activity of IFITM1 by inhibiting the late stages of HCV entry, possibly in a coordinated manner by trapping the virion in the endosomal pathway and targeting it for degradation at the lysosome (PubMed: 26354436 ). ( IFM1_HUMAN,P13164 ) Gene Wiki entry for … lifeguard plusWebPubMed mcphs career centerWebInterferon-induced transmembrane proteins (IFITMs) are broad spectrum antiviral factors that inhibit the entry of a wide range of clinically important pathogens including influenza A virus, HIV-1, and Dengue virus. IFITMs are thought to act primarily by antagonizing virus-cell membrane fusion in thi … life guard plus size swimsuitsWebIn addition, IFITM2 would be a potential target for treating GC and other malignant tumors. Interferon-induced transmembrane protein 2 promotes epithelial-mesenchymal transition … lifeguard plus symbol